Protecting your beloved pets from a myriad of parasites is a crucial aspect of their overall health and well-being. Revolution® and Revolution® Plus are topical treatments designed to offer comprehensive protection against common and dangerous parasites for both cats and dogs. This article delves into what these medications are used for, how they work, important considerations for their use, and how to administer them effectively.
What Parasites Do Revolution® and Revolution® Plus Target?
Revolution®, with its active ingredient selamectin, is a versatile treatment effective against several common parasites. For both cats and dogs, it provides protection against flea infestations and prevents heartworm disease.
In cats, Revolution® extends its protective umbrella to include the treatment and control of ear mites, roundworm infections, and hookworm infections. For dogs, it also targets ear mites, sarcoptic mange, and infestations of the American dog tick. Revolution® is approved for use in cats and kittens from 8 weeks of age and older, and for dogs and puppies from 6 weeks of age and older.
Revolution® Plus, specifically formulated for cats, also contains selamectin, offering the same protection against fleas and heartworm disease. However, Revolution® Plus is enhanced with a second active ingredient, sarolaner, which provides additional benefits. This dual-action formula allows Revolution® Plus to treat and control ear mites, roundworm, and hookworm infections. Furthermore, it effectively combats the Blacklegged tick, Gulf Coast tick, and American dog tick, while also providing robust flea protection. Revolution® Plus is indicated for cats and kittens that are at least 8 weeks old and weigh at least 2.8 pounds.
Key Considerations for Using Revolution® and Revolution® Plus
When administering Revolution® or Revolution® Plus, several factors are important to keep in mind:
- General Health: These medications should not be used on sick, debilitated, or underweight animals.
- Reproductive Safety: Revolution® has been tested and found to be safe for use in pregnant and lactating female cats and dogs, as well as breeding males and females. The safe use of Revolution® Plus in breeding, pregnant, or lactating cats had not been fully evaluated at the time of publication, so caution is advised.
- Neurological Sensitivity: Revolution® Plus should be used with caution in cats with a history of neurological disorders.
- Concurrent Treatments: If your cat is receiving another flea or parasite preventative, consult your veterinarian before using Revolution® Plus.
How These Medications Combat Parasites
The mechanism of action for Revolution® and Revolution® Plus involves targeting the nervous systems of the parasites.
The active ingredient in Revolution® is selamectin. Selamectin works by disrupting the electrolyte balance within the nerve and muscle cells of parasites like heartworms. This disruption leads to paralysis and subsequent death of the parasite.
Revolution® Plus combines selamectin with sarolaner. Sarolaner is a member of the isoxazoline class of medications. Isoxazolines function by overstimulating the nervous system of fleas and ticks, causing paralysis and death. Revolution® Plus begins to kill fleas present on your pet within hours of administration, offering rapid relief.
Application Guidelines for Revolution® and Revolution® Plus
Adhering to the correct application method is vital for the efficacy and safety of these treatments. Always follow the specific directions on the drug label or as instructed by your veterinarian.
- Dosage and Frequency: Revolution® and Revolution® Plus are administered once monthly. It is crucial to maintain a consistent schedule, applying the product as close to every 30 days as possible.
- Correct Product: Using the wrong product for the species or an incorrect dosage based on weight can lead to a lack of efficacy or even an overdose, posing serious risks. Never use cat medications on dogs or vice versa.
- Application Site:
- For dogs, part the fur between the shoulder blades and apply the entire contents of the applicator directly to the skin.
- For cats, apply the medication at the base of the neck.
- Important Precautions:
- Do not apply to wet fur or skin.
- After application, you may notice temporary effects such as stiff or clumping hair, hair discoloration, or a powdery residue at the application site.
- Wait two hours after applying Revolution® or Revolution® Plus before bathing your dog. For cats, wait 24 hours before bathing.
- Prevent your pet from ingesting the medication.
What to Do If a Dose is Missed
If you forget to administer a dose, give it as soon as you remember. However, maintain the schedule as close to every 30 days as possible for subsequent doses. If your veterinarian has prescribed a different dosing schedule, consult them for guidance if a dose is missed. Never administer extra or double doses.
Potential Side Effects
While side effects are uncommon, owners should be aware of potential reactions.
In Cats and Dogs:
- Irritation or hair loss at the application site
- Vomiting
- Diarrhea
- Decreased appetite
- Lethargy
- Drooling
- Increased breathing rate
- Tremors
- Conjunctivitis (cats)
- Sneezing (cats)
- Fever
- Generalized itching or hives
- Lack of coordination
- Seizures (dogs)
Specific to Revolution® Plus: As Revolution® Plus contains sarolaner, a type of isoxazoline, there is a potential, though uncommon, risk of neurologic side effects in cats. These may include muscle tremors, stumbling, incoordination, collapse, and seizures.
Human Side Effects
Revolution® and Revolution® Plus are veterinary prescription medications and are not intended for human use. Never administer medication intended for pets to humans, or vice versa.
To minimize the risk of human side effects, avoid direct contact with the treated area on your pet until it is completely dry. Wash your hands thoroughly after application. In rare cases, humans may experience skin reactions such as hives, itching, or redness. If accidental ingestion, eye contact, or a skin reaction occurs, contact your physician or the national Poison Control Center at 800-222-1222.
Monitoring and Veterinary Consultation
Your veterinarian may recommend testing your cat for existing heartworm infections before starting treatment with Revolution® or Revolution® Plus, particularly if they are over 6 months old. Cats with adult heartworms can still use these medications to prevent further infection. Similarly, it is recommended that all dogs be tested for heartworm disease before initiating Revolution® treatment. Dogs with existing infections should be treated to eliminate adult heartworms prior to starting Revolution®. Your veterinarian may suggest other monitoring or routine tests based on your pet’s individual health needs.
When to Contact Your Veterinarian
Seek veterinary advice if you observe any of the following:
- Severe side effects
- Your pet’s condition worsens or fails to improve
- Signs of an overdose
- Any additional questions or concerns regarding the use of these medications
Overdose Information
Overdoses can be more severe in dogs with the MDR1 (ABCG1) gene defect. Topical overdoses typically do not present additional symptoms beyond those listed under side effects. However, oral ingestion of these medications can lead to more severe symptoms in cats. If you suspect an overdose, the wrong product was used, or the topical product was accidentally ingested, contact your veterinarian immediately, seek emergency veterinary care, or call an animal poison control center.
Storage Recommendations
Proper storage ensures the medication remains effective and safe:
- Always check the product label for specific storage requirements.
- Store Revolution® products at controlled room temperatures below 86°F (30°C).
- Keep away from heat and open flames.
- Until ready for administration, keep the medication in its original container to protect it from moisture and light.
- Ensure the medication is stored out of reach of children and pets.
Frequently Asked Questions
Can I use Revolution® for dogs on my cat?
No. It is critical to use the correct medication formulated for the specific species and appropriate for your pet’s weight. The dosage and formulation differ between dogs and cats for Revolution®.
Do I need a prescription for Revolution®?
Yes, Revolution® is a prescription-only medication. Working closely with your veterinarian is essential to establish the most effective parasite prevention plan tailored to your pet’s individual needs.
Do indoor cats need Revolution®?
Yes. Even indoor-only cats are susceptible to parasite infestations. Revolution® offers comprehensive protection against external parasites like fleas, ticks, and ear mites, as well as internal parasites such as heartworms, roundworms, and hookworms, making it a valuable preventative measure for all cats.
